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ACE, a tool to predict the stereochemical outcome of reactions

 Asymmetric Catalyst Evaluation

 

- TS is a linear combination of reactants and products (Hammond postulate)

 

 Applications and Validations:

    - Application to Diels-Alder cycloadditions
    - Application to Organocatalyzed Aldol reactions
    - Validation with Sharpless AD

 

 

 
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