Obtaining the software

The FORECASTER Suite

Formerly known as the FITTED Suite, the FORECASTER Suite is distributed free to non-commercial organizations in return of bugs reporting and testing/validating studies.

In order to obtain FITTED, we need to receive the license agreement and the information form duly signed and complete. After we receive the signed license agreement, you will be granted the permissions to the privileged download section.

academic license agreement.

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The FORECASTER Web Platform

For more information about licensing options or to obtain an evaluation version of the FORECASTER Web Platform, please contact us.

You can test the webserver version from the demo page here. In order to gain access to the platform, you need to sign the license agreement. and send a copy to info@fitted.ca. After we receive the signed license agreement, you will be provided with a login and password for the FORECASTER Platform.

Please visit Molecular Forecaster for further information on licensing or research contracts.

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Documentation

  • FORECASTER Suite 2016 User Guide: FORECASTER-Suite-2016_UserGuide.pdf
  • FORECASTER Suite 2016 docking tutorial: FORECASTER-Suite-2016_Tutorial-Docking.pdf
  • FORECASTER Suite 2016 metabolism tutorial: FORECASTER-Suite-2016_Tutorial-Metabolism.pdf
  • FORECASTER Suite 2016 virtual chemist tutorial: FORECASTER-Suite-2016_Tutorial-Virtual-Chemist.pdf
  • FORECASTER Suite 2016 pharmacophore search tutorial: FORECASTER-Suite-2016_Tutorial-Pharmacophore-Search.pdf

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    References

    Please cite the following papers
    FITTED:

    Corbeil C.R., Englebienne P., Moitessier N. Docking ligands into flexible and solvated macromolecules. 1. Development and validation of FITTED 1.0 "Journal of Chemical Information and Modeling" (2007), 47, 2, 435-449 link
    Corbeil C.R., Moitessier N. Docking ligands into flexible and solvated macromolecules. 3. Impact of input ligand conformation, protein flexibility, and water molecules on the accuracy of docking programs "Journal of Chemical Information and Modeling" (2009), 49, 4, 997-1009 link

    FORECASTER:

    Therrien E., Englebienne P., Arrowsmith A.G., Mendoza-Sanchez R., Corbeil C.R., Weill N., Campagna-Slater V., Moitessier N. Integrating medicinal chemistry, organic/combinatorial chemistry, and computational chemistry for the discovery of selective estrogen receptor modulatorswith FORECASTER, a novel platform for drug discovery "Journal of Chemical Information and Modeling" (2012), 52, 1, 210-224 link

    IMPACTS:

    Campagna-Slater V., Pottel J., Therrien E., Cantin L.-D., Moitessier N. Development of a computational tool to rival experts in the prediction of sites of metabolism of xenobiotics by P450s "Journal of Chemical Information and Modeling" (2012), 52, 9, 2471-2483 link

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    System Requirements

    Minimum requirements:

    • Windows XP, Vista, 7/8/10 (32-bit and 64-bit architecture)
    • 1 GB of RAM (4GB or more recommended)
    • Java 1.6 (latest version) for gui
    • Linux (32-bit and 64-bit architecture) and higher versions
    • 1 GB of RAM (4GB or more recommended)
    • Java 1.6 (latest version) for gui
    • Leopard 10.6 (64-bit architecture only) and higher versions
    • 1GB of RAM (4 GB or more recommended)
    • Java 1.6 (latest version) for gui
    • Xterm needs to be installed (XQuartz project)

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